Hi Qdiabetes: Diamicron MR is a long acting tablet with a slow onset, the medication reaches peak action in 6 hours. For this reason, you can take your daily dose either before or after breakfast.
Because the long action, most people benefit 24 hours control on their blood glucose especially when taken in combination with other glucose lowering medications. However in a small number of individuals, their blood glucose levels start to climb in the evening so they may require a small second dose.
In order to find out how your blood glucose levels improve with this medication, consider doing more frequent blood glucose testing. Be sure to discuss the results with your diabetes health care team.